The headliner in U.S. motorcycle road racing is the highly competitive AMA Chevy Trucks U.S. Superbike Championship. Superbikes are racing motorcycles that are modified versions of four-stroke machines originally sold for street use. The concept of Superbike racing is similar to that of championship stock car racing--to have machines that visually resemble production models, while allowing freedom of the tuner to improve the power and handling characteristics of the machine.

The Superbike class permits 750cc four-cylinder engines, and twin-cylinder engines up to 1,000cc displacement. The four cylinder engines are used by Kawasaki, Suzuki and Yamaha. Twin-cylinder marques include championship-winning Ducati, the Harley-Davidson VR1000 and the Honda RC51, which debuted in 2000.

Superbike Qualifying procedure:
For timed qualifying events in Superbike and classes requiring an Expert license, a rider's best lap time must be within 115% of the fastest qualifying rider's best lap time in order to pre-qualify for one of the available grid positions in the final.

Riders in the top-10 in points of a particular class, currently or at the end of the previous season, will be permitted a total of one provisional start per season in that class. Provided the grid is not full, this will allow such riders to be placed on the back row of the grid should they not qualify through the normal procedure. Riders will not be permitted provisional starts in more than one class in a season.

The final race is 100 kilometers in length, except at the Daytona 200, where the race is 200 miles.